Can using herbal tea lead to resistance to artemisinin?

This is contradicted by the historical use of the plant by the Chinese for centuries without any resistance being observed.

1 – It is much more difficult for mosquitoes to develop resistance to a polytherapy rather than to an isolated molecule.

2 – Artemisia afra, which does not contain artemisinin, has shown the same efficacy as Artemisia annua. Studies are in progress.